Karakis designed dozens of combined heat and power plants. She prepared general plans for housing construction and designed furniture sets for mass production and interiors for schools, hotels, apartments and restaurants. She became a member of the Council of Art and Technology of Ukraine in 1970. Together with Valentyna Shevchenko, she restored the refectory of St. Michael’s Monastery in Kyiv (1973-1982). Among her other projects are:

• Thermal power plants (Boiler plant of MGSS factory, Kyiv, 1954, coauthor); general plan of the residential area and  thermal power plant in Mohyliv-Podilskiy (1954); thermal power plant in Tekeli, Kazakhstan (1954-1956); thermal power plant in Almaty, Kazakhstan (1954-1956); thermal power plant in Berdichev (1958-1962))
• Restaurants (“Gostiny Dvor” (interior and bar). Kyiv (1988); “Eastern” (Kyiv, 1994); restaurant in the hotel “Dnepropetrovsk” Kyiv; “For Two Hares” on St. Andrew’s Descent, Kyiv)
• Hotels (Interiors and furniture of the Gradetskaya Hotel, Chernihiv (1979); interiors of the hotel “Theatrical”  Vladimirskaya street, Kyiv (1979); interiors and equipment of the rest house “Avangard” in Nemirov (1982); interiors of the Zhytomyr Hotel, Zhytomyr (1983); interiors of the hotel “Dnepropetrovsk” Dnipro (1985); interiors and furniture of the Black Sea Hotel, Odessa; interiors of the hotel “Rus,” Kyiv)
• Furniture (sectional rack furniture, series K-58-117 (1958). Prize of the 1st All-Union Furniture Competition in Moscow in 1958; furniture for the Wedding Palace (Central Registry Office) in Kyiv (1960); aset of furniture with the use of bent-stamped elements (1961). Prize of the II All-Union Competition in Moscow and many others)

Karakis was also a prolific author, whose publications focused on interior design (see Bibliography).